Keyphrases
Precision Medicine
100%
N-methyl-D-aspartate Receptor (NMDAR)
100%
Receptor-targeted Therapy
100%
Encephalopathy
100%
GRIN2D
100%
N-methyl-D-aspartate Receptor Antagonist
33%
Gain-of-function mutation
33%
Glutamate
33%
Synaptic
16%
Epilepsy
16%
Mechanistic Understanding
16%
Genetic mutation
16%
Seizure
16%
Fold Increase
16%
Overactivation
16%
Receptor Gene
16%
FDA-approved Drugs
16%
Ligand-gated Cation Channel
16%
Moderate to Severe
16%
Neurotoxicity
16%
Transmembrane Domain
16%
Channel Gating
16%
Epileptic Encephalopathy
16%
Disease-causing mutations
16%
GluN2B
16%
Antiepileptic Drugs
16%
Childhood Epilepsy
16%
Neuronal Cell Death
16%
Excitatory Synaptic Transmission
16%
Exome
16%
Complementary DNA (cDNA)
16%
Ketamine
16%
Cultured Neurons
16%
Proton
16%
Deactivation
16%
Receptor Subunits
16%
Glycine
16%
Magnesium
16%
Receptor Sensitivity
16%
Proband
16%
Epilepsy Therapy
16%
Memantine
16%
Open Probability
16%
Seizure Burden
16%
Heterozygous Missense mutation
16%
Negative Modulators
16%
New-onset Refractory Status Epilepticus (NORSE)
16%
Electroclinical Syndrome
16%
Panel Sequencing
16%
Medicine and Dentistry
Brain Disease
100%
N Methyl-D-Aspartate Receptor
100%
Personalized Medicine
100%
NMDA Receptor
100%
Targeted Therapy
100%
Glutamic Acid
40%
Gain of Function Mutation
40%
NMDA Receptor Antagonist
40%
Epileptic Seizure
40%
Ketamine
20%
Missense Mutation
20%
Receptor Subunit
20%
Genetic Transfection
20%
Magnesium
20%
Excitotoxicity
20%
Receptor Gene
20%
Gene Mutation
20%
Nerve Cell Culture
20%
Channel Gating
20%
Status Epilepticus
20%
Epilepsy Syndromes
20%
Benign Childhood Epilepsy
20%
Synaptic Transmission
20%
Cation Channel
20%
Memantine
20%
Receptor Sensitivity
20%
Epilepsy Therapy
20%
Cell Death
20%
Exome
20%
Complementary DNA
20%
Diseases
20%
Neuroscience
Aspartic Acid
100%
NMDA Receptor
100%
Brain Disease
100%
Receptor
80%
Glutamic Acid
40%
Gain of Function Mutation
40%
NMDA Receptor Antagonist
40%
Complementary DNA
20%
Transfection
20%
Ketamine
20%
Neuronal Cell Death
20%
Memantine
20%
Epilepsy Therapy
20%
Pediatric Epilepsy
20%
Gene Mutation
20%
Receptor Gene
20%
Cation Channel
20%
Excitotoxicity
20%
Missense Mutation
20%
Receptor Subunit
20%
Channel Gating
20%
Synaptic Transmission
20%
Status Epilepticus
20%
Anticonvulsant
20%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Brain Disease
100%
N Methyl Dextro Aspartic Acid Receptor
100%
Aspartic Acid
100%
NMDA Receptor Antagonist
40%
Glutamic Acid
40%
Syndrome
20%
Benign Childhood Epilepsy
20%
Ketamine
20%
Receptor Subunit
20%
Epileptic State
20%
Excitotoxicity
20%
Cation Channel
20%
Complementary DNA
20%
Memantine
20%
Diseases
20%
Biochemistry, Genetics and Molecular Biology
NMDA Receptor
100%
Aspartic Acid
100%
Gain of Function Mutation
28%
Receptor Antagonist
28%
Glutamic Acid
28%
Transmembrane Domain
14%
Proband
14%
Exome
14%
Excitotoxicity
14%
Gene Mutation
14%
Receptor Gene
14%
Channel Gating
14%
Transfection
14%
Nerve Cell Culture
14%
Missense Mutation
14%
Receptor Sensitivity
14%
Cell Death
14%
Synaptic Transmission
14%