Predication of reflex recovery after stroke using quantitative assessments of motor impairment at 1 month

M. M. Mirbagheri, W. Z. Rymer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

The objective of this study was to characterize the time-course of changes reflex stiffness after stroke, and to use the Fugl-Meyer Assessment (FMA) at 1 month to predict the ensuing recovery patterns over 1 year. We quantified the modulation of reflex stiffness as a function of elbow joint angles at 1, 2, 3, 6, and 12 months after stroke, using a parallel cascade system identification technique. We then used the "growth mixture" and logistic regression models to characterize recovery patterns over 1 year and to predict these patterns, based on the FMA score at 1 month. We observed two major distinct recovery classes for the relationship between reflex stiffness and elbow angle. The FMA at 1 month was a significant predictor of reflex stiffness as a function of elbow angle at different time points in the first year. The logistical regression class membership may enable us to accurately predict reflex behavior during the first year, information of great potential value for planning targeted therapeutic interventions. Finally, the findings suggest that abnormal reflex function could contribute to functional motor impairment.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages7252-7255
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

Keywords

  • Natural history
  • Prediction
  • Reflex
  • Stiffness
  • Stroke recovery

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

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