Predicting backscatter characteristics from micron- And submicron- Scale ultrasound contrast agents using a size-integration technique

Hairong Zheng; Alexander Barker; Robin Shandas

doi:10.1109/TUFFC.2006.1610573

Predicting backscatter characteristics from micron- And submicron- Scale ultrasound contrast agents using a size-integration technique

Hairong Zheng^*, Alexander Barker, Robin Shandas

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

In this paper, a computationally, inexpensive, size-integration method based on a modified Rayleigh-Plesset model is developed to predict backscatter spectra from groups of bubbles with various size distributions, incident acoustic amplitudes, and driving frequencies. The method was validated using experimentally measured spectra from contrast bubbles of various sizes: Optison®, Levovist®, ST68® microbubbles, and submicron bubbles. This method provides a computationally inexpensive means of examining backscatter spectrum from multiple bubbles, especially in predicting occurrence and relative amplitude of subharmonics and second harmonics.

Original language	English (US)
Pages (from-to)	639-644
Number of pages	6
Journal	IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Volume	53
Issue number	3
DOIs	https://doi.org/10.1109/TUFFC.2006.1610573
State	Published - Mar 1 2006

ASJC Scopus subject areas

Instrumentation
Acoustics and Ultrasonics
Electrical and Electronic Engineering

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abstract = "In this paper, a computationally, inexpensive, size-integration method based on a modified Rayleigh-Plesset model is developed to predict backscatter spectra from groups of bubbles with various size distributions, incident acoustic amplitudes, and driving frequencies. The method was validated using experimentally measured spectra from contrast bubbles of various sizes: Optison{\textregistered}, Levovist{\textregistered}, ST68{\textregistered} microbubbles, and submicron bubbles. This method provides a computationally inexpensive means of examining backscatter spectrum from multiple bubbles, especially in predicting occurrence and relative amplitude of subharmonics and second harmonics.",

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Predicting backscatter characteristics from micron- And submicron- Scale ultrasound contrast agents using a size-integration technique. / Zheng, Hairong; Barker, Alexander; Shandas, Robin.

In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 53, No. 3, 01.03.2006, p. 639-644.

Research output: Contribution to journal › Article › peer-review

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