Predicting Death From Renal Failure in Primary Hypertension

Larry Z. Goss, Robert M F Rosa, William M. O'brien, Carlos R. Ayers, J. Edwin Wood*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


After a retrospective study of 174 individuals who died from chronic primary hypertension, it was found that prediction of death from renal failure could be quantitated on the basis of initial measurement of the systolic blood pressure, cardiac-thoracic ratio, blood urea, and age at the time of initial diagnosis. The group with renal failure had massive cardiomegaly and very contracted kidneys. One half of the population was Negro, but the natural history of their hypertension was not convincingly different from the white group. If initial clinical observations are substituted in the discriminant equation, D=-1.5(age at onset) + 3(percent cardiac-thoracic ratio) + 0.5(systolic blood pressure) + 1(blood urea), and D is greater than 249, 85% of patients died of renal failure. If D is less than 249, 85% of patients died of causes other than renal failure.

Original languageEnglish (US)
Pages (from-to)160-164
Number of pages5
JournalArchives of Internal Medicine
Issue number2
StatePublished - Jan 1 1969

ASJC Scopus subject areas

  • Internal Medicine


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