Predicting the outcome of melanoma: Can we tell the future of a patient's melanoma?

Oriol Y�lamos, Pedram Gerami*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Cutaneous melanoma is responsible for the greatest number of skin cancer related deaths. For many years there were few therapeutic options. However, in the last years a number of new therapeutic options have emerged showing improved survival rates for advanced melanoma patients. A significant question based on these findings is whether identification and treatment of patients with biologically aggressive melanomas at an earlier clinical stage offer an opportunity for even greater improvement in overall survival. In this review, we will discuss the recent advancements in molecular strategies beyond traditional staging to identify biologically aggressive melanomas, and which are their implications in terms of predicting the prognosis of patients with melanoma.

Original languageEnglish (US)
Pages (from-to)217-224
Number of pages8
JournalMelanoma Management
Volume2
Issue number3
DOIs
StatePublished - Jan 1 2015

Keywords

  • Comparative genomic hybridization
  • FISH
  • Gene-expression profiling
  • Melanoma
  • Next-generation sequencing
  • Prognosis
  • Sentinel lymph node biopsy

ASJC Scopus subject areas

  • Oncology
  • Dermatology

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