Prediction of breast cancer size by ultrasound, mammography and core biopsy

M. Golshan, B. B. Fung, E. Wiley, J. Wolfman, A. Rademaker, Monica Morrow*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Neoadjuvant chemotherapy and non-surgical tumor ablation rely upon imaging studies to determine tumor size. In this study the accuracy of ultrasound (US) mammography and core biopsy in determining tumor size was examined in 202 patients with Stages I and II breast cancer. The most accurate single modality for determining tumor size was mammography with a correlation coefficient® of 0.66, followed by US (r=0.48) and core biopsy (r=0.28). Size measurements were less accurate in lobular than ductal cancers. The combination of the three modalities understaged 25% of the tumors >1 cm in size, and overstaged 10% of those <1 cm. The inability to accurately determine tumor size has important implications for the use of non-surgical ablation.

Original languageEnglish (US)
Pages (from-to)265-271
Number of pages7
Issue number4
StatePublished - Aug 2004


  • Breast cancer staging
  • Non-surgical ablation
  • Preoperative size

ASJC Scopus subject areas

  • Surgery


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