Predictive value sensitivity, and specificity of ultrasonic targeted imaging for fetal anomalies in gravid women at high risk for birth defects

Rudy E. Sabbagha*, Zubie Sheikh, Ralph K Tamura, Sharon DalCompo, Joe Leigh Simpson, Richard Depp, Albert B. Gerbie

*Corresponding author for this work

Research output: Contribution to journalArticle

71 Scopus citations

Abstract

In this report the predictive value of ultrasonic targeted imaging for fetal anomalies (TIFFA) is defined. Six hundred fifteen pregnant women at high risk for birth defects were scanned from January, 1980, to December, 1983. Follow-up evaluation was available on 569 fetuses. The pregnancies were classified into five groups according to the indications used for ultrasonic targeted imaging studies. The largest number of women were placed in group 1 and were referred because of a variety of abnormalities in previous or ongoing pregnancies. The women classified in the other four groups were examined because of maternal or fetal reasons related to specific craniospinal (29%), urinary (7.9%), gastrointestinal (6.7%), and skeletal (3.7%) defects. In our series the predictive values of abnormal and normal ultrasonic targeted imaging studies were 95% and 99%, respectively. A detailed breakdown of the accuracy of ultrasonic targeted imaging in relation to each anatomic category is presented; these data are useful in counseling gravid women with anomalous fetuses.

Original languageEnglish (US)
Pages (from-to)822-827
Number of pages6
JournalAmerican journal of obstetrics and gynecology
Volume152
Issue number7
DOIs
StatePublished - Jan 1 1985

Keywords

  • Accuracy of ultrasound
  • fetal anomalies

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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