Predictors of postoperative complications from stress urinary incontinence procedures: a NSQIP database study

Introduction and hypothesis: There are few studies examining patient risk factors for postoperative complications following midurethral sling (MUS) placement for stress urinary incontinence (SUI). The objective of this study was to describe 30-day postoperative complications after MUS using the National Surgical Quality Improvement Program database. Secondary objectives included rates of readmission and patient factors associated with postoperative complications and readmissions following MUS. Methods: We identified 16,491 women who underwent MUS for SUI between 2014 and 2018. American Society of Anesthesia (ASA) classification, medical comorbidities, readmission, reoperation, and 30-day postoperative complications were extracted. Outcomes included the 30-day postoperative complications, readmission, and reoperations. Descriptive statistics, univariate analyses, and multivariate logistic regression were used. Results: The majority of patients were white (66.9%) and had an ASA classification II (60.9%). Postoperative complications occurred in 4.2% of patients; 1.5% required readmission and 1.0% required reoperation. The most common complication was urinary tract infection (3.4%). Using multivariate logistic regression, older age, i.e., ≥80 years of age, was associated with increased odds of complication (aOR 1.77, 95%CI 1.14–2.72) and readmission (aOR 3.84, 95%CI 1.76–8.66). ASA class III and IV were associated with increased odds of complications (aOR 1.55, 95%CI 1.13–2.14, and aOR 3.06, 95% CI 1.48–5.86 respectively) and readmissions. Women of Asian, American Indian or Alaska Native, and Native Hawaiian or Pacific Islander descent (“other”) were associated with increased postoperative complications (aOR 1.51, 95%CI 1.07–2.07). Conclusion: Postoperative complications following MUS are rare. Factors associated with complications following MUS for SUI include age, ASA class, and women of “other” race.