Predictors of PTSD in mothers of children undergoing bone marrow transplantation: The role of cognitive and social processes

Sharon Manne*, Katherine DuHamel, Nancy Nereo, Jamie Ostroff, Susan Parsons, Richard Martini, Sharon Williams, Laura Mee, Sandra Sexson, Lisa Wu, Joanne Difede, William H. Redd

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

76 Scopus citations

Abstract

Objective: To investigate the role of cognitive and social processing in posttraumatic stress symptoms and disorder (PTSD) among mothers of children undergoing bone marrow and hematopoietic stem-cell transplantation (BMT/SCT). Method: Questionnaires assessing emotional distress, BMT-related fears, and negative responses of family and friends were completed by 90 mothers at the time of the BMT infusion and 3 and 6 months post-BMT. PTSD symptoms were measured 6 months post-BMT by both paper-and-pencil and structured interview methods. Results: Emotional distress, BMT-related fears, and negative responses of family and friends assessed at the time of BMT hospitalization were predictive of later PTSD symptoms. None of these variables prospectively predicted a PTSD diagnosis as measured by the structured interview. Conclusions: Higher levels of general psychological distress, cognitive interpretations of the threat of the BMT for the child's future functioning, and negative responses of family and friends may place mothers at risk for post-BMT posttraumatic stress symptomatology.

Original languageEnglish (US)
Pages (from-to)607-617
Number of pages11
JournalJournal of pediatric psychology
Volume27
Issue number7
DOIs
StatePublished - Oct 2002

Keywords

  • Mothers
  • Pediatric bone marrow transplantation
  • Posttraumatic stress disorder
  • Psychological distress

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology

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