Preliminary framework for familiar auditory sensory training (FAST) provided during coma recovery

Theresa Louise Bender Pape, Joshua M. Rosenow, Brett Harton, Vijaya Patil, Ann Guernon, Todd Parrish, Kathleen Froehlich, Catherine Burress, Shane McNamee, Amy A. Herrold, Bessie Weiss, Xue Wang

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Since there remains a need to examine the nature of the neural effect and therapeutic efficacy/effectiveness of sensory stimulation provided to persons in states of seriously impaired consciousness, a passive sensory stimulation intervention, referred to as the Familiar Auditory Sensory Training (FAST) protocol, was developed for examination in an ongoing, double-blind, randomized clinical trial (RCT). The FAST protocol is described in this article according to the preliminary framework, which is a synthesis of knowledge regarding principles of plasticity and capabilities of the human brain to automatically and covertly process sensory input. Feasibility issues considered during the development of the intervention are also described. To enable replication of this intervention, we describe procedures to create the intervention and lessons learned regarding the creation process. The potential effect of the intervention is illustrated using functional brain imaging of nondisabled subjects. This illustration also demonstrates the relevance of the rationale for designing the FAST protocol. To put the intervention within the context of the scientific development process, the article culminates with a description of the study design for the ongoing RCT examining the efficacy of the FAST protocol.

Original languageEnglish (US)
Pages (from-to)1137-1152
Number of pages16
JournalJournal of rehabilitation research and development
Volume49
Issue number7
DOIs
StatePublished - Nov 5 2012

    Fingerprint

Keywords

  • Auditory stimulation
  • Coma
  • Disordered or impaired consciousness
  • Minimally conscious state
  • Plasticity
  • Rehabilitation
  • Story
  • Traumatic brain injury
  • Treatment
  • Vegetative state

ASJC Scopus subject areas

  • Rehabilitation

Cite this