Premenstrual dysphoric disorder and changes in frontal alpha asymmetry

Elsa Baehr*, Peter Rosenfeld, Laura Miller, Rufus Baehr

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Objective: Since the clinical picture of premenstrual dysphoric disorder (PMDD) in the Luteal phase of the menstrual cycle is characterized by extreme negative affect, we predicted and obtained a change in frontal cortical EEG alpha asymmetry, which has been shown to be an index of affect. Method: We observed two monthly cycles for five women diagnosed as having PMDD and one monthly cycle for five non-PMDD control subjects. Results: Asymmetry percent scores for the five PMDD women, and for the five control subjects before and after the Luteal phase were typically within the normal non-depressed range, however the asymmetry scores for the PMDD group fell into the negative range during the Luteal period while the control subjects remained stable. Discussion: We predicted alpha asymmetry scores would be affected by the luteal phase in PMDD cases. This hypothesis was clearly confirmed.

Original languageEnglish (US)
Pages (from-to)159-167
Number of pages9
JournalInternational Journal of Psychophysiology
Issue number2
StatePublished - Apr 2004


  • Alpha asymmetry
  • Depression
  • EEG biofeedback
  • Neurofeedback
  • Premenstrual dysphoric disorder

ASJC Scopus subject areas

  • General Neuroscience
  • Neuropsychology and Physiological Psychology
  • Physiology (medical)


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