Prenatal depression and birth mode sequentially mediate maternal education's influence on infant sleep duration

CHILD study investigators

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Rationale: Sleep duration is critical to growth, learning, and immune function development in infancy. Strategies to ensure that national recommendations for sleep duration in infants are met require knowledge of perinatal factors that affect infant sleep. Objectives: To investigate the mechanistic pathways linking maternal education and infant sleep. Methods: An observational study was conducted on 619 infants whose mothers were enrolled at the Edmonton site of the CHILD birth cohort. Infant sleep duration at three months was assessed using the Brief Infant Sleep Questionnaire. Maternal education was collected via maternal report. Prenatal and postnatal depression scores were obtained from the 20-item Center for Epidemiologic Studies Depression Scale (CES-D). Birth records and maternal report were the source of covariate measures. Mediation analysis (PROCESS v3.0)was used to examine the indirect effects of maternal education on infant sleep duration mediated through prenatal depression and birth mode. Measurements and main results: At three months of age, infants slept on average 14.1 h. Lower maternal education and prenatal depression were associated with significantly shorter infant sleep duration. Emergency cesarean section birth was associated with 1-hour shorter sleep duration at three months compared to vaginal birth [without intrapartum antibiotic prophylaxis](β: −0.99 h; 95% CI: −1.51, −0.48). Thirty percent of the effect of lower maternal education on infant total sleep duration was mediated sequentially through prenatal depression and birth mode (Total Indirect Effects: −0.12, 95% CI: −0.22, −0.03, p < 0.05). Conclusions: Prenatal depression and birth mode sequentially mediate the effect of maternal education on infant sleep duration.

Original languageEnglish (US)
Pages (from-to)24-32
Number of pages9
JournalSleep Medicine
Volume59
DOIs
StatePublished - Jul 1 2019

Keywords

  • Birth mode
  • Emergency caesarean section
  • Maternal education
  • Pediatric sleep
  • Prenatal depression

ASJC Scopus subject areas

  • Medicine(all)

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