Preparation and biodistribution of new apoptosis imaging regent 99mTc-FM-2

Shundong Ji*, Wei Fang, Jundong Zhou, Zuoxiang He, Xiujie Liu, Changgeng Ruan, Ming Zhao

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

FM-2 was modified with 2-iminotholane and labeled with 99Tcm-GH. The radiochemical purity of 99mTc-FM-2 was over 95% and can stable in the routine temperature for more than 8 hours. Biodistribution in mice showed 99mTc-FM-2 was cleared mainly by liver and kidney. The normal myocardial showed a high uptake and rapid clearance of 99mTc-FM-2.

Original languageEnglish (US)
Pages (from-to)679-682
Number of pages4
JournalHe Jishu/Nuclear Techniques
Volume30
Issue number8
StatePublished - Aug 1 2007

Keywords

  • Apoptosis
  • Biodistribution
  • Synaptotagmin I
  • Technetium

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering

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