@article{13d1d986cca44acdba75c6b6e189ad8d,
title = "Preparation and use of wireless reprogrammable multilateral optogenetic devices for behavioral neuroscience",
abstract = "Wireless battery-free optogenetic devices enable behavioral neuroscience studies in groups of animals with minimal interference to natural behavior. Real-time independent control of optogenetic stimulation through near-field communication dramatically expands the realm of applications of these devices in broad contexts of neuroscience research. Dissemination of these tools with advanced functionalities to the neuroscience community requires protocols for device manufacturing and experimental implementation. This protocol describes detailed procedures for fabrication, encapsulation and implantation of recently developed advanced wireless devices in head- and back-mounted forms. In addition, procedures for standard implementation of experimental systems in mice are provided. This protocol aims to facilitate the application of wireless optogenetic devices in advanced optogenetic experiments involving groups of freely moving rodents and complex environmental designs. The entire protocol lasts ~3–5 weeks.",
author = "Yiyuan Yang and Mingzheng Wu and Wegener, {Amy J.} and Abraham V{\'a}zquez-Guardado and Efimov, {Andrew I.} and Ferrona Lie and Taoyi Wang and Yuhang Ma and Anthony Banks and Zhengwei Li and Zhaoqian Xie and Yonggang Huang and Good, {Cameron H.} and Yevgenia Kozorovitskiy and Rogers, {John A.}",
note = "Funding Information: This work utilized Northwestern University Micro/Nano Fabrication Facility (NUFAB), which is partially supported by Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the Materials Research Science and Engineering Center (DMR-1720139), the State of Illinois, and Northwestern University. C.H.G. is supported by the LUCI program, sponsored by the Basic Research Office, Office of Under Secretary of Defense for Research and Engineering (USD R&E). Y.K. is supported by the NIH R01MH117111 and R01NS107539, and Beckman Young Investigator Award. M.W is supported as an affiliate fellow of the NIH T32 AG20506 and 2021 Christina Enroth-Cugell and David Cugell Fellow. Z.X. acknowledges the support from the National Natural Science Foundation of China (grant no. 12072057), LiaoNing Revitalization Talents Program (grant no. XLYC2007196) and Fundamental Research Funds for the Central Universities (grant no. DUT20RC(3)032). Y.H. acknowledges support from NSF (CMMI1635443). Funding Information: This work utilized Northwestern University Micro/Nano Fabrication Facility (NUFAB), which is partially supported by Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the Materials Research Science and Engineering Center (DMR-1720139), the State of Illinois, and Northwestern University. C.H.G. is supported by the LUCI program, sponsored by the Basic Research Office, Office of Under Secretary of Defense for Research and Engineering (USD R&E). Y.K. is supported by the NIH R01MH117111 and R01NS107539, and Beckman Young Investigator Award. M.W is supported as an affiliate fellow of the NIH T32 AG20506 and 2021 Christina Enroth-Cugell and David Cugell Fellow. Z.X. acknowledges the support from the National Natural Science Foundation of China (grant no. 12072057), LiaoNing Revitalization Talents Program (grant no. XLYC2007196) and Fundamental Research Funds for the Central Universities (grant no. DUT20RC(3)032). Y.H. acknowledges support from NSF (CMMI1635443). Publisher Copyright: {\textcopyright} 2022, Springer Nature Limited.",
year = "2022",
month = apr,
doi = "10.1038/s41596-021-00672-5",
language = "English (US)",
volume = "17",
pages = "1073--1096",
journal = "Nature Protocols",
issn = "1754-2189",
publisher = "Nature Publishing Group",
number = "4",
}