Preparation of 3-aryl-substituted salicylaldehydes via Suzuki coupling

Michael A. Zhuravel, Sonbinh T. Nguyen

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

An efficient method for the preparation of 3-arylsalicylaldehydes by palladium-catalyzed cross-coupling reaction of arylboronic acids and 3-bromo-5-tert-butylsalicylaldehyde is described. Parallel catalyst screening allowed rapid optimization of the reaction conditions.

Original languageEnglish (US)
Pages (from-to)7925-7928
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number45
DOIs
StatePublished - Nov 5 2001

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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