An efficient method for the preparation of 3-arylsalicylaldehydes by palladium-catalyzed cross-coupling reaction of arylboronic acids and 3-bromo-5-tert-butylsalicylaldehyde is described. Parallel catalyst screening allowed rapid optimization of the reaction conditions.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Nov 5 2001|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry