Abstract
A procedure for preparing 14C-labelled half-generation Starburst® PAMAM dendrimers is described. Controlled incorporation of radioisotope was achieved by Michael additions of amines with 14C-labelled methyl acrylate, resulting in dendrimers with specific activities between 30 and 45 mCi/mmol in very high radiochemical purity.
Original language | English (US) |
---|---|
Pages (from-to) | 935-939 |
Number of pages | 5 |
Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
Volume | 41 |
Issue number | 10 |
DOIs | |
State | Published - Oct 1998 |
Keywords
- C-labelled half-generation Starburst® PAMAM dendrimers
- Synthesis
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Radiology Nuclear Medicine and imaging
- Drug Discovery
- Spectroscopy
- Organic Chemistry