Abstract
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are common conditions with a rising burden. Yet there are significant management gaps between clinical guidelines and practice in patients with NAFLD and NASH. Further, there is no single global guiding strategy for the management of NAFLD and NASH. The American Gastroenterological Association, in collaboration with 7 professional associations, convened an international conference comprising 32 experts in gastro-enterology, hepatology, endocrinology, and primary care providers from the United States, Europe, Asia, and Australia. Conference content was informed by the results of a national NASH Needs Assessment Survey. The participants reviewed and dis-cussed published literature on global burden, screening, risk stratification, diagnosis, and management of individuals with NAFLD, including those with NASH. Participants identified promising approaches for clinical practice and prepared a comprehensive, unified strategy for primary care providers and relevant specialists encompassing the full spectrum of NAFLD/NASH care. They also identified specific high-yield targets for clinical research and called for a unified, international public health response to NAFLD and NASH.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2162-2172 |
| Number of pages | 11 |
| Journal | Diabetes care |
| Volume | 44 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1 2021 |
Funding
This article is based on a conference sponsored by the American Gastroenterological Association (AGA), with the financial support of independent medical education grants from Intercept Pharmaceuticals, Inc, Pfizer Inc, Allergan, and GENFIT, and the support of the following collaborating medical associations: American Association of Clinical Endocrinologists, American Academy of Family Physicians, American Association for the Study of Liver Diseases, American College of Osteopathic Family Physicians, American Diabetes Association, Endocrine Society, and The Obesity Society. The authors are grateful for the contributions of the participants in the July 2020 conference, who are listed, tog-ether with affiliations, in the Supplementary Material. F.K. is a member at the Center for Innovations in Quality, Effectiveness and Safety (CIN-13-413), Michael E. DeBakey VA Medical Center, Houston, Texas. In addition, the authors acknowledge Dr. Anya Karavanov for her assistance with the NASH Needs Assessment Survey, Dr. Terra Ziporyn, medical editor, for her assistance with the manuscript, and Alissa Effland for her assistance with the manuscript’s graphics.
ASJC Scopus subject areas
- Advanced and Specialized Nursing
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
