Preprostate Biopsy Rectal Culture and Postbiopsy Sepsis

Aisha Khalali Taylor*, Adam Bryant Murphy

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Transrectal ultrasound-guided biopsy of the prostate (TRUSP) remains the primary procedure for the accurate histologic diagnosis of prostate cancer. Fluoroquinolones (FQs) are still recommended as the agents of choice for antimicrobial prophylaxis for TRUSP despite the alarming increasing incidence of FQ-resistant organisms among men undergoing TRUSP. This article reviews the current TRUSP antimicrobial prophylaxis guidelines, antimicrobial resistance and its implications for these guidelines, the incidence of post-TRUSP infectious complications including urosepsis, the seminal data supporting pre-TRUSP rectal swab (RS), RS technique and protocol, and the current available literature surrounding the efficacy of RS in reducing post-TRUSP infectious complications.

Original languageEnglish (US)
Pages (from-to)449-458
Number of pages10
JournalUrologic Clinics of North America
Issue number4
StatePublished - Nov 2015


  • Biopsy
  • Drug resistance
  • Prostate
  • Rectal swab
  • Targeted antimicrobial prophylaxis
  • Urosepsis

ASJC Scopus subject areas

  • Urology


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