Abstract
Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1124-1125 |
| Number of pages | 2 |
| Journal | Nature Medicine |
| Volume | 15 |
| Issue number | 10 |
| DOIs | |
| State | Published - Nov 4 2009 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Preserving fertility during cancer treatment. / Woodruff, Teresa K.
In: Nature Medicine, Vol. 15, No. 10, 04.11.2009, p. 1124-1125.Research output: Contribution to journal › Short survey
TY - JOUR
T1 - Preserving fertility during cancer treatment
AU - Woodruff, Teresa K
PY - 2009/11/4
Y1 - 2009/11/4
N2 - Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.
AB - Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.
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UR - http://www.scopus.com/inward/citedby.url?scp=70350435644&partnerID=8YFLogxK
U2 - 10.1038/nm1009-1124
DO - 10.1038/nm1009-1124
M3 - Short survey
C2 - 19812566
AN - SCOPUS:70350435644
VL - 15
SP - 1124
EP - 1125
JO - Nature Medicine
JF - Nature Medicine
SN - 1078-8956
IS - 10
ER -