Preserving fertility during cancer treatment

Research output: Contribution to journalShort survey

25 Citations (Scopus)

Abstract

Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.

Original languageEnglish (US)
Pages (from-to)1124-1125
Number of pages2
JournalNature Medicine
Volume15
Issue number10
DOIs
StatePublished - Nov 4 2009

Fingerprint

Oncology
Fertility
Germ Cells
Cisplatin
Cells
Neoplasms
Trademarks
Names
Imatinib Mesylate

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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abstract = "Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.",
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Preserving fertility during cancer treatment. / Woodruff, Teresa K.

In: Nature Medicine, Vol. 15, No. 10, 04.11.2009, p. 1124-1125.

Research output: Contribution to journalShort survey

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