Preserving fertility during cancer treatment

Teresa K. Woodruff

doi:10.1038/nm1009-1124

Preserving fertility during cancer treatment

Teresa K. Woodruff

Obstetrics and Gynecology

Research output: Contribution to journal › Short survey › peer-review

26 Scopus citations

Abstract

Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.

Original language	English (US)
Pages (from-to)	1124-1125
Number of pages	2
Journal	Nature Medicine
Volume	15
Issue number	10
DOIs	https://doi.org/10.1038/nm1009-1124
State	Published - 2009

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1038/nm1009-1124

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abstract = "Imatinib (trade name Gleevec) preserves fertility in female mice treated with the common chemotherapeutic agent cisplatin. Imatinib seems to block an apoptotic pathway activated by cisplatin in ovarian germ cells (pages 1179-1185). The findings could lead to new ways to protect germ cells from the damaging effects of cancer treatment.",

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