Pressure modes of invasive mechanical ventilation

Benjamin D. Singer*, Thomas C. Corbridge

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Pressure modes of invasive mechanical ventilation generate a tidal breath by delivering pressure over time. Pressure control ventilation (PC) is the prototypical pressure mode and is patient- or time-triggered, pressure-limited, and time-cycled. Other pressure modes include pressure support ventilation (PSV), pressure-regulated volume control (PRVC, also known as volume control plus [VC+]), airway pressure release ventilation (APRV), and biphasic ventilation (also known as BiLevel). Despite their complexity, modern ventilators respond to patient effort and respiratory system mechanics in a fairly predictable fashion. No single mode has consistently demonstrated superiority in clinical trials; however, empiric management with a pressure mode may achieve the goals of patient-ventilator synchrony, effective respiratory system support, adequate gas exchange, and limited ventilator-induced lung injury.

Original languageEnglish (US)
Pages (from-to)701-709
Number of pages9
JournalSouthern Medical Journal
Issue number10
StatePublished - Oct 1 2011

ASJC Scopus subject areas

  • General Medicine


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