Presynaptic inhibition in the striatum of the basal ganglia improves pattern classification and thus promotes superior goal selection

David J. Schwab; James C. Houk

doi:10.3389/fnsys.2015.00152

Presynaptic inhibition in the striatum of the basal ganglia improves pattern classification and thus promotes superior goal selection

David J. Schwab, James C. Houk^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

This review article takes a multidisciplinary approach to understand how presynaptic inhibition in the striatum of the basal ganglia (BG) contributes to pattern classification and the selection of goals that control behavior. It is a difficult problem both because it is multidimensional and because it is has complex system dynamics. We focus on the striatum because, as the main site for input to the BG, it gets to decide what goals are important to consider.

Original language	English (US)
Article number	152
Journal	Frontiers in Systems Neuroscience
Volume	9
Issue number	DEC
DOIs	https://doi.org/10.3389/fnsys.2015.00152
State	Published - Dec 15 2015

Funding

DJS was partially supported by NIH Grant No. K25 GM098875-02.

Keywords

Basal ganglia
Pattern classification
Presynaptic inhibition
Schizophrenia
Striatum

ASJC Scopus subject areas

Cellular and Molecular Neuroscience
Cognitive Neuroscience
Developmental Neuroscience
Neuroscience (miscellaneous)

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10.3389/fnsys.2015.00152

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title = "Presynaptic inhibition in the striatum of the basal ganglia improves pattern classification and thus promotes superior goal selection",

abstract = "This review article takes a multidisciplinary approach to understand how presynaptic inhibition in the striatum of the basal ganglia (BG) contributes to pattern classification and the selection of goals that control behavior. It is a difficult problem both because it is multidimensional and because it is has complex system dynamics. We focus on the striatum because, as the main site for input to the BG, it gets to decide what goals are important to consider.",

keywords = "Basal ganglia, Pattern classification, Presynaptic inhibition, Schizophrenia, Striatum",

author = "Schwab, {David J.} and Houk, {James C.}",

note = "Funding Information: DJS was partially supported by NIH Grant No. K25 GM098875-02. Publisher Copyright: {\textcopyright} 2015 Schwab and Houk.",

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AU - Houk, James C.

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AB - This review article takes a multidisciplinary approach to understand how presynaptic inhibition in the striatum of the basal ganglia (BG) contributes to pattern classification and the selection of goals that control behavior. It is a difficult problem both because it is multidimensional and because it is has complex system dynamics. We focus on the striatum because, as the main site for input to the BG, it gets to decide what goals are important to consider.

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KW - Pattern classification

KW - Presynaptic inhibition

KW - Schizophrenia

KW - Striatum

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Presynaptic inhibition in the striatum of the basal ganglia improves pattern classification and thus promotes superior goal selection

Abstract

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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