TY - JOUR
T1 - Pretreatment of high-risk patients requiring radiographic contrast media studies
AU - Greenberger, Paul A.
AU - Patterson, Roy
AU - Simon, Ronald
AU - Lieberman, Philip
AU - Wallace, Warren
N1 - Funding Information:
Fmm rhc Sections of Allergy-Immunology, Department of Medi-;ine, Northwestern University Medical School, Chicago; Scripps Clinic and Research Foundation, La Jolla; and University of ‘l~nnes6ee. Memphis. Stqorted by U.S. Public Health Service grants Al 11403 and AI 10386 and the Ernest S. Bazley Grant. Received for publication Aug. 25, 1980. Acrrspted for publication Oct. 17, 1980. Re@rint requests to: Paul A. Grccnbcrger, M.D., Northwestern University Medical School, 303 East Chicago Ave., Chicago, IL 60611.
PY - 1981/3
Y1 - 1981/3
N2 - Pretreatment for 318 radiographic contrast media procedures in 284 patients with a prior anaphylactoid reaction to radiographic contrast media was associated with no adverse effects in 294 (92.5%) procedures. In 23 procedures (7.1%), mild or minimal reactions occurred that were of little or no consequence to the patient. One (0.3%) patient experienced transient hypotension, wheezing, and urticaria. The pretreatment program consisted of prednisone 50 mg orally every 6 hr for three doses ending 1 hr before the procedure and diphenhydramine 50 mg intramuscularly 1 hr before the procedure. Based on the cumulative results in the prospective series of 318 procedures, this regimen is appropriate prophylaxis for high-risk patients.
AB - Pretreatment for 318 radiographic contrast media procedures in 284 patients with a prior anaphylactoid reaction to radiographic contrast media was associated with no adverse effects in 294 (92.5%) procedures. In 23 procedures (7.1%), mild or minimal reactions occurred that were of little or no consequence to the patient. One (0.3%) patient experienced transient hypotension, wheezing, and urticaria. The pretreatment program consisted of prednisone 50 mg orally every 6 hr for three doses ending 1 hr before the procedure and diphenhydramine 50 mg intramuscularly 1 hr before the procedure. Based on the cumulative results in the prospective series of 318 procedures, this regimen is appropriate prophylaxis for high-risk patients.
UR - http://www.scopus.com/inward/record.url?scp=0019504533&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019504533&partnerID=8YFLogxK
U2 - 10.1016/0091-6749(81)90059-2
DO - 10.1016/0091-6749(81)90059-2
M3 - Article
C2 - 7462535
AN - SCOPUS:0019504533
SN - 0091-6749
VL - 67
SP - 185
EP - 187
JO - The Journal of allergy and clinical immunology
JF - The Journal of allergy and clinical immunology
IS - 3
ER -