Prevalence of hepatitis B virus infection among pregnant women in Jos, Nigeria

Francis Ajang Magaji*, Mark Ojogba Okolo, Z. Hassan, Iornum H. Shambe, Victor Chung Pam, Amaka Ngozi Ocheke, Esther S. Yiltok, Williams Golit, Stephen Ajen Anzaku, Martins Daloek, Jerry Ogwuche, Godwin E. Imade, Christain Isichie, Jsiah T. Mutihir, Stephen Oguche, Oche Agbaji, Jonah Musa, Solomon Ateine Sagay, A. I. Zoakah, Susan E. Cohn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objectives: The study sought to determine the prevalence and risk factors associated with Hepatitis B surface antigenemia (HBsAg) positivity among pregnant women in Jos, Nigeria. Methodology: This was a cross-sectional study carried out among the pregnant population in five healthcare facilities in Jos, between November 1, 2017 and April 30, 2018. Informed consent was obtained, and data on sociodemographic and risk factors for hepatitis B virus (HBV) infection were collected. Hepatitis B viral infection was assessed using the in vitro HBsAg diagnostic rapid kit (Acon Laboratories, USA). Descriptive statistics, Chi-square test, and logistic regression were performed to identify predictors of HBV infection in the study population. All statistical analyses were carried out on STATA version 15. Results: Of the 3,238 women enrolled, 7.4% (241/3238) (95% confidence interval [CI] = 6.6% to 8.4%) were HBsAg positive. The absence of HBV vaccination (adjusted odds ratio [AOR] = 2.49; 95% CI = 1.49-4.09; P < 0.001), co-infection with HIV (AOR = 1.90; 95% CI = 1.18-3.08; P = 0.009), and higher parity (AOR = 1.37; 95% CI = 1.04-1.79; P = 0.024) were independently associated with HBV infection in pregnancy. Conclusions: The prevalence of HBV infection among pregnant women was high, especially among those without prior vaccination for HBV, those with HIV co-infection and higher parity.

Original languageEnglish (US)
Pages (from-to)176-181
Number of pages6
JournalAnnals of African Medicine
Issue number3
StatePublished - Jul 1 2020


  • Hepatitis-B virus infection
  • Nigeria
  • pregnancy
  • prevalence

ASJC Scopus subject areas

  • Medicine(all)


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