TY - JOUR
T1 - Prevalence of hepatitis B virus infection among pregnant women in Jos, Nigeria
AU - Magaji, Francis Ajang
AU - Okolo, Mark Ojogba
AU - Hassan, Z.
AU - Shambe, Iornum H.
AU - Pam, Victor Chung
AU - Ocheke, Amaka Ngozi
AU - Yiltok, Esther S.
AU - Golit, Williams
AU - Anzaku, Stephen Ajen
AU - Daloek, Martins
AU - Ogwuche, Jerry
AU - Imade, Godwin E.
AU - Isichie, Christain
AU - Mutihir, Jsiah T.
AU - Oguche, Stephen
AU - Agbaji, Oche
AU - Musa, Jonah
AU - Sagay, Solomon Ateine
AU - Zoakah, A. I.
AU - Cohn, Susan E.
N1 - Funding Information:
The research reported in this publication was supported by the Fogarty International Centre of the National Institutes of Health and also the Office of the Director, National Institutes of Health (OD), National Institute of Nursing Research, and the National Institutes of Neurological Disorders and Stroke under award number D43TW010130. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Funding Information:
The research reported in this publication was supported by the Fogarty International Centre of the National Institutes of Health and also the Offce of the Director, National Institutes of Health (OD), National Institute of Nursing Research, and the National Institutes of Neurological Disorders and Stroke under award number D43TW010130. The content is solely the responsibility of the authors and does not necessarily represent the offcial views of the National Institutes of Health.
Publisher Copyright:
© 2020 Annals of African Medicine Published by Wolters Kluwer-Medknow.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Objectives: The study sought to determine the prevalence and risk factors associated with Hepatitis B surface antigenemia (HBsAg) positivity among pregnant women in Jos, Nigeria. Methodology: This was a cross-sectional study carried out among the pregnant population in five healthcare facilities in Jos, between November 1, 2017 and April 30, 2018. Informed consent was obtained, and data on sociodemographic and risk factors for hepatitis B virus (HBV) infection were collected. Hepatitis B viral infection was assessed using the in vitro HBsAg diagnostic rapid kit (Acon Laboratories, USA). Descriptive statistics, Chi-square test, and logistic regression were performed to identify predictors of HBV infection in the study population. All statistical analyses were carried out on STATA version 15. Results: Of the 3,238 women enrolled, 7.4% (241/3238) (95% confidence interval [CI] = 6.6% to 8.4%) were HBsAg positive. The absence of HBV vaccination (adjusted odds ratio [AOR] = 2.49; 95% CI = 1.49-4.09; P < 0.001), co-infection with HIV (AOR = 1.90; 95% CI = 1.18-3.08; P = 0.009), and higher parity (AOR = 1.37; 95% CI = 1.04-1.79; P = 0.024) were independently associated with HBV infection in pregnancy. Conclusions: The prevalence of HBV infection among pregnant women was high, especially among those without prior vaccination for HBV, those with HIV co-infection and higher parity.
AB - Objectives: The study sought to determine the prevalence and risk factors associated with Hepatitis B surface antigenemia (HBsAg) positivity among pregnant women in Jos, Nigeria. Methodology: This was a cross-sectional study carried out among the pregnant population in five healthcare facilities in Jos, between November 1, 2017 and April 30, 2018. Informed consent was obtained, and data on sociodemographic and risk factors for hepatitis B virus (HBV) infection were collected. Hepatitis B viral infection was assessed using the in vitro HBsAg diagnostic rapid kit (Acon Laboratories, USA). Descriptive statistics, Chi-square test, and logistic regression were performed to identify predictors of HBV infection in the study population. All statistical analyses were carried out on STATA version 15. Results: Of the 3,238 women enrolled, 7.4% (241/3238) (95% confidence interval [CI] = 6.6% to 8.4%) were HBsAg positive. The absence of HBV vaccination (adjusted odds ratio [AOR] = 2.49; 95% CI = 1.49-4.09; P < 0.001), co-infection with HIV (AOR = 1.90; 95% CI = 1.18-3.08; P = 0.009), and higher parity (AOR = 1.37; 95% CI = 1.04-1.79; P = 0.024) were independently associated with HBV infection in pregnancy. Conclusions: The prevalence of HBV infection among pregnant women was high, especially among those without prior vaccination for HBV, those with HIV co-infection and higher parity.
KW - Hepatitis-B virus infection
KW - Nigeria
KW - pregnancy
KW - prevalence
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U2 - 10.4103/aam.aam_20_19
DO - 10.4103/aam.aam_20_19
M3 - Article
C2 - 32820729
AN - SCOPUS:85089768929
VL - 19
SP - 176
EP - 181
JO - Annals of African Medicine
JF - Annals of African Medicine
SN - 1596-3519
IS - 3
ER -
