Prevalence of measles antibodies in asymptomatic human immunodeficiency virus-infected adults

B. E. Sha, A. A. Harris*, C. A. Benson, W. L. Atkinson, P. A. Urbanski, J. A. Stewart, W. W. Williams, R. L. Murphy, J. P. Phair, S. A. Levin, H. A. Kessler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

One hundred five asymptomatic human immunodeficiency virus-seropositive adults were screened for measles antibody. Ages ranged from 21 to 59 years (mean, 35.7). CD4+ lymphocyte counts (range, 76-1137/mm3), percentage of CD4+ cells (6-42), CD4:CD8 ratio (0.08-1.3), measles antibody titers by EIA, and undocumented history of prior measles or immunization were obtained. Forty-six patients gave a history of measles but no immunization, 18 of immunization but no measles, 26 of immunization and measles, and 15 of neither measles nor vaccination. Only one patient (<1%) lacked levels of antibody considered protective. Neither the presence nor the level of antibody were predictable from patient age, history of measles or immunization, CD4+ lymphocyte count, percentage of CD4+ cells, or CD4:CD8 ratio. Nearly all subjects had antibody to measles, regardless of immunization or measles history. Whether these antibodies are truly protective is unknown.

Original languageEnglish (US)
Pages (from-to)973-975
Number of pages3
JournalJournal of Infectious Diseases
Volume164
Issue number5
DOIs
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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