TY - JOUR
T1 - Prevalence of periodontal diseases in a multicenter cohort of perinatally HIV-infected and HIV-exposed and uninfected youth
AU - Ryder, Mark I.
AU - Yao, Tzy Jyun
AU - Russell, Jonathan S.
AU - Moscicki, Anna Barbara
AU - Shiboski, Caroline H.
AU - Yang, Ester
AU - Shearer, William
AU - Paul, Mary
AU - Cooper, Norma
AU - Harris, Lynette
AU - Kemp-Posterman, Karen
AU - Wun, Selene
AU - Purswani, Murli
AU - Baig, Mahboobullah
AU - Cintron, Anna
AU - Zeni, Jennifer
AU - Puga, Ana
AU - Navarro, Sandra
AU - Patton, Doyle
AU - Leon, Deyana
AU - Wai Ng, Man
AU - Burchett, Sandra
AU - Karthas, Nancy
AU - Kammerer, Betsy
AU - Jurado, Ray
AU - Kuttab, Johnny
AU - Vorachek, Ashlee
AU - Yogev, Ram
AU - Ann Sanders, Margaret
AU - Malee, Kathleen
AU - Hunter, Scott
AU - Badner, Victor
AU - Garreett, Ronald
AU - Wiznia, Andrew
AU - Burey, Marlene
AU - Nozyce, Molly
AU - Chialastri, Susan
AU - Chen, Janet
AU - Ivey, Latreca
AU - Bulkley, Maria Garcia
AU - Grant, Mitzie
AU - Gonzalez, Ramon
AU - Acevedo-Flores, Midnela
AU - Rios, Heida
AU - Olivera, Vivian
AU - Townsend, Janice
AU - Silio, Margarita
AU - Jones, Medea
AU - Sirois, Patricia
AU - Gandhi, Roopa
AU - the Pediatric HIV/AIDS Cohort Study
N1 - Funding Information:
The following institutions, clinical site investigators and staff participated in conducting the Pediatric HIV/AIDS Cohort Study Adolescent Master Protocol in 2012, in alphabetical order: Baylor College of Medicine: Ester Yang*, William Shearer, Mary Paul, Norma Cooper, Lynette Harris; Bronx Lebanon Hospital Center: Karen Kemp-Posterman*, Selene Wun*, Murli Purswani, Mahboobullah Baig, Anna Cintron; Children's Diagnostic and Treatment Center: Jennifer Zeni*, Ana Puga, Sandra Navarro, Doyle Patton, Deyana Leon; Children's Hospital, Boston: Man Wai Ng*, Sandra Burchett, Nancy Karthas, Betsy Kammerer; Ann and Robert H. Lurie Children's Hospital of Chicago: Ray Jurado*, Johnny Kuttab*, Ashlee Vorachek*, Ram Yogev, Margaret Ann Sanders, Kathleen Malee, Scott Hunter; Jacobi Medical Center: Victor Badner*, Ronald Garreett*, Andrew Wiznia, Marlene Burey, Molly Nozyce; St. Christopher's Hospital for Children: Susan Chialastri*, Janet Chen, Latreca Ivey, Maria Garcia Bulkley, Mitzie Grant; San Juan Hospital/Department of Pediatrics: Ramon Gonzalez*, Midnela Acevedo-Flores, Heida Rios, Vivian Olivera; Tulane University Health Sciences Center: Janice Townsend*, Margarita Silio, Medea Jones, Patricia Sirois; University of Colorado Denver Health Sciences Center: Roopa Gandhi*, Elizabeth McFarland, Emily Barr, Robin McEvoy; University of Medicine and Dentistry of New Jersey: Kenneth Markowitz*, Arry Dieudonne, Linda Bettica, Susan Adubato; the authors thank the children and families for their participation in PHACS, and the individuals and institutions involved in the conduct of PHACS. *Participating Dentist.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Aims: To compare the prevalence and severity of periodontal diseases between 180 perinatally HIV-infected (PHIV) and 118 perinatally HIV-exposed and uninfected (PHEU) youth in a cross-sectional study conducted at 11 clinical sites in the United States and Puerto Rico from the Adolescent Master Protocol study of the Pediatric HIV/AIDS cohort study (PHACS) network. Methods: Several analyses were conducted, employing the current CDC/AAP classification for periodontitis and incorporating a definition of gingivitis based on a bleeding on probing (BOP) threshold, and analyses based on more detailed whole-mouth, intra-oral regionally, site-based and tooth-based criteria of BOP, plaque levels, pockets depths and clinical attachment levels. Results: After adjusting for plaque control habits and behavioural and sociodemographic factors, there were no significant differences in periodontal diseases between the PHIV and PHEU youth using any of these criteria. For PHIV youth, there was no significant association between parameters of periodontal disease and current HIV status. Conclusions: Although no significant differences in periodontal parameters were noted between the PHIV and PHEU youth, the influence of antiretroviral therapy merits further exploration in this cohort in a longitudinal study.
AB - Aims: To compare the prevalence and severity of periodontal diseases between 180 perinatally HIV-infected (PHIV) and 118 perinatally HIV-exposed and uninfected (PHEU) youth in a cross-sectional study conducted at 11 clinical sites in the United States and Puerto Rico from the Adolescent Master Protocol study of the Pediatric HIV/AIDS cohort study (PHACS) network. Methods: Several analyses were conducted, employing the current CDC/AAP classification for periodontitis and incorporating a definition of gingivitis based on a bleeding on probing (BOP) threshold, and analyses based on more detailed whole-mouth, intra-oral regionally, site-based and tooth-based criteria of BOP, plaque levels, pockets depths and clinical attachment levels. Results: After adjusting for plaque control habits and behavioural and sociodemographic factors, there were no significant differences in periodontal diseases between the PHIV and PHEU youth using any of these criteria. For PHIV youth, there was no significant association between parameters of periodontal disease and current HIV status. Conclusions: Although no significant differences in periodontal parameters were noted between the PHIV and PHEU youth, the influence of antiretroviral therapy merits further exploration in this cohort in a longitudinal study.
KW - HIV
KW - gingivitis
KW - periodontal disease
KW - youth
UR - http://www.scopus.com/inward/record.url?scp=85005916233&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85005916233&partnerID=8YFLogxK
U2 - 10.1111/jcpe.12646
DO - 10.1111/jcpe.12646
M3 - Article
C2 - 27801947
AN - SCOPUS:85005916233
VL - 44
SP - 2
EP - 12
JO - Journal of Clinical Periodontology
JF - Journal of Clinical Periodontology
SN - 0303-6979
IS - 1
ER -