Prevalence of periodontal diseases in a multicenter cohort of perinatally HIV-infected and HIV-exposed and uninfected youth

Mark I. Ryder*, Tzy Jyun Yao, Jonathan S. Russell, Anna Barbara Moscicki, Caroline H. Shiboski, Ester Yang, William Shearer, Mary Paul, Norma Cooper, Lynette Harris, Karen Kemp-Posterman, Selene Wun, Murli Purswani, Mahboobullah Baig, Anna Cintron, Jennifer Zeni, Ana Puga, Sandra Navarro, Doyle Patton, Deyana LeonMan Wai Ng, Sandra Burchett, Nancy Karthas, Betsy Kammerer, Ray Jurado, Johnny Kuttab, Ashlee Vorachek, Ram Yogev, Margaret Ann Sanders, Kathleen Malee, Scott Hunter, Victor Badner, Ronald Garreett, Andrew Wiznia, Marlene Burey, Molly Nozyce, Susan Chialastri, Janet Chen, Latreca Ivey, Maria Garcia Bulkley, Mitzie Grant, Ramon Gonzalez, Midnela Acevedo-Flores, Heida Rios, Vivian Olivera, Janice Townsend, Margarita Silio, Medea Jones, Patricia Sirois, Roopa Gandhi, the Pediatric HIV/AIDS Cohort Study

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Aims: To compare the prevalence and severity of periodontal diseases between 180 perinatally HIV-infected (PHIV) and 118 perinatally HIV-exposed and uninfected (PHEU) youth in a cross-sectional study conducted at 11 clinical sites in the United States and Puerto Rico from the Adolescent Master Protocol study of the Pediatric HIV/AIDS cohort study (PHACS) network. Methods: Several analyses were conducted, employing the current CDC/AAP classification for periodontitis and incorporating a definition of gingivitis based on a bleeding on probing (BOP) threshold, and analyses based on more detailed whole-mouth, intra-oral regionally, site-based and tooth-based criteria of BOP, plaque levels, pockets depths and clinical attachment levels. Results: After adjusting for plaque control habits and behavioural and sociodemographic factors, there were no significant differences in periodontal diseases between the PHIV and PHEU youth using any of these criteria. For PHIV youth, there was no significant association between parameters of periodontal disease and current HIV status. Conclusions: Although no significant differences in periodontal parameters were noted between the PHIV and PHEU youth, the influence of antiretroviral therapy merits further exploration in this cohort in a longitudinal study.

Original languageEnglish (US)
Pages (from-to)2-12
Number of pages11
JournalJournal of Clinical Periodontology
Issue number1
StatePublished - Jan 1 2017


  • HIV
  • gingivitis
  • periodontal disease
  • youth

ASJC Scopus subject areas

  • Periodontics


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