Prevention, Diagnosis, and Management of Radiation-Associated Cardiac Disease: JACC Scientific Expert Panel

Milind Y. Desai*, Stephan Windecker, Patrizio Lancellotti, Jeroen J. Bax, Brian P. Griffin, Oren Cahlon, Douglas R. Johnston

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

90 Scopus citations

Abstract

Radiation-associated cardiac disease, a heterogeneous and complex disease, manifests years or even decades following radiation exposure to the chest. It is associated with a significantly higher morbidity and mortality. Often, the presentation is vague and overlaps with many diseases, presenting unique diagnostic and management issues. As a result, a high index of suspicion followed by multimodality imaging is crucial, along with comprehensive screening to enable early detection. Timing of intervention should be carefully considered in these patients, because surgery is often complex with an emerging role of percutaneous interventions.

Original languageEnglish (US)
Pages (from-to)905-927
Number of pages23
JournalJournal of the American College of Cardiology
Volume74
Issue number7
DOIs
StatePublished - Aug 20 2019

Keywords

  • cardiac disease
  • diagnosis
  • management
  • radiation
  • review

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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