Prevention of hypergranulation tissue after gastrostomy tube placement: A randomised controlled trial of hydrocolloid dressings

Astrid H. León, Ferdynand Hebal, Christine Stake, Kerry Baldwin, Katherine A. Barsness*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Hypergranulation tissue formation is a common complication after gastrostomy tube (G-tube) placement, occurring in 44%–68% of children. Hydrocolloid dressings are often used in the treatment of hypergranulation tissue but have not been studied for the prevention of postoperative hypergranulation tissue. An institutional review board (IRB)-approved, prospective, randomised study was performed in paediatric patients who underwent G-tube placement at a single, large children's hospital from January 2011 to November 2016. After placement, patients were randomly assigned to (1) standard postoperative G-tube care, (2) standard hydrocolloid G-tube dressing, or (3) silver-impregnated hydrocolloid G-tube dressing, and the incidences of postoperative hypergranulation tissue formation, tube dislodgement, infection, and emergency department use were compared. A total of 171 patients were enrolled; 128 patients (75%) had at least 4 months of follow up and were included in the analyses. Eighty-nine patients (69.5%) developed hypergranulation tissue during the postoperative period, with no significant differences in incidence among the three treatment arms. Of those who developed hypergranulation tissue, 46 (56%) visited the emergency department, compared with 6 of the 39 patients (19%) who did not develop hypergranulation tissue. Hydrocolloid dressings (standard or silver-impregnated) do not prevent the development of hypergranulation tissue or other complications after G-tube placement in paediatric patients.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalInternational Wound Journal
Issue number1
StatePublished - Feb 1 2019


  • children
  • gastrostomy tube
  • hydrocolloid dressings
  • hypergranulation tissue

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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