Prevention of sepsis in children: A new paradigm for public policy

Carley Riley, Derek S. Wheeler*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Sepsis is one of the leading causes of death worldwide. While the management of critically ill patients with sepsis is certainly better now compared to 20 years ago, sepsis-associated mortality remains unacceptably high. Annual deaths from sepsis in both children and adults far surpass the number of deaths from acute myocardial infarction (AMI), stroke, or cancer. Given the substantial toll that sepsis takes worldwide, prevention of sepsis remains a global priority. Multiple effective prevention strategies exist. Antibiotic prophylaxis, immunizations, and healthcare quality improvement initiatives are important means through which we may reduce the morbidity and mortality from sepsis around the world. Inclusion of these strategies in a coordinated and thoughtful campaign to reduce the global burden of sepsis is necessary for the improvement of pediatric health worldwide.

Original languageEnglish (US)
Article number437139
JournalCritical Care Research and Practice
StatePublished - 2012

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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