Priapism associated with iloperidone: A case report

Lisette A. Rodriguez-Cabezas*, Betty Y. Kong, Gaurava Agarwal

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Priapism is a known side effect of antipsychotics. The causal mechanism seems to be mediated through α1-adrenergic receptor blockade which many antipsychotics are known to possess. We present the first detailed case of iloperidone-induced priapism in a patient with bipolar disorder with psychotic features. His case highlights some of the important risk factors clinicians should consider when using iloperidone, as it may be the highest-risk antipsychotic for causing priapism given it is a very potent blocker of the alpha-adrenergic receptor.

Original languageEnglish (US)
Pages (from-to)451.e5-451.e6
JournalGeneral Hospital Psychiatry
Issue number4
StatePublished - Jul 2014


  • Antipsychotics
  • Bipolar
  • Iloperidone
  • Priapism
  • Psychosis

ASJC Scopus subject areas

  • Psychiatry and Mental health


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