Primary acinic cell carcinoma of the breast.

Eric A. Elster*, Jennifer Markusic, Russell Ball, Peter Soballe, Michael Henry, Adeline Louie, Susan Clare

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Acinic cell carcinoma (ACC) is an uncommon neoplasm of the salivary glands with low malignant potential. Even rarer is the occurrence of primary ACC of the breast, there is only one previously documented case. We now describe the second case of a primary carcinoma of the breast with morphological, ultrastructural, and immunohistochemical features consistent with an ACC. In contrast to the previous case report we report the lack of encapsulation of the tumor and a spectrum of cell types within the tumor including cells resembling well-differentiated infiltrating ductal carcinoma. Additionally we did not observe the abundant nuclear abnormalities noted in the previously published case. We report for the first time the mucicarmine-staining pattern of this tumor as well as immunohistochemistry directed against cytokeratin 7, the estrogen receptor, and the progesterone receptor.

Original languageEnglish (US)
Pages (from-to)993-995
Number of pages3
JournalThe American surgeon
Volume68
Issue number11
StatePublished - Nov 2002

ASJC Scopus subject areas

  • Surgery

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