Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis

Rimas V. Lukas*, Roger Stupp, Vinai Gondi, Jeffrey J. Raizer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Primary central nervous system (CNS) lymphoma is a rare CNS neoplasm. Its highest incidence is in the elderly and the immunocompromised. The initial steps in establishing a diagnosis involve CNS imaging. Familiarity with the clinical presentation is important in order to limit the risk of a nondiagnostic biopsy. In addition to confirming the diagnosis, it is wise to evaluate for extra-CNS disease. There are important differences in the presentation and evaluation of immunocompetent patients and those of immunocompromised patients; we will delineate these in this review. Appropriate initial clinical evaluations facilitate optimal therapeutic management for patients with primary CNS lymphoma. This is of particular importance because primary CNS lymphoma is a potentially curable disease, despite the high likelihood of recurrence.

Original languageEnglish (US)
Pages (from-to)17-27
Number of pages11
JournalONCOLOGY (United States)
Volume32
Issue number1
StatePublished - 2018

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint

Dive into the research topics of 'Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis'. Together they form a unique fingerprint.

Cite this