Primary central nervous system lymphoma: Part 1: Epidemiology, diagnosis, staging, and prognosis

Rimas Vincas Lukas*, Roger Stupp, Vinai Gondi, Jeffrey J Raizer

*Corresponding author for this work

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Primary central nervous system (CNS) lymphoma is a rare CNS neoplasm. Its highest incidence is in the elderly and the immunocompromised. The initial steps in establishing a diagnosis involve CNS imaging. Familiarity with the clinical presentation is important in order to limit the risk of a nondiagnostic biopsy. In addition to confirming the diagnosis, it is wise to evaluate for extra-CNS disease. There are important differences in the presentation and evaluation of immunocompetent patients and those of immunocompromised patients; we will delineate these in this review. Appropriate initial clinical evaluations facilitate optimal therapeutic management for patients with primary CNS lymphoma. This is of particular importance because primary CNS lymphoma is a potentially curable disease, despite the high likelihood of recurrence.

Original languageEnglish (US)
Pages (from-to)17-27
Number of pages11
JournalONCOLOGY (United States)
Volume32
Issue number1
StatePublished - Jan 1 2018

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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