Primary cutaneous alveolar rhabdomyosarcoma of the perineum

Yun Gong, Jerome Chao, Bruce Bauer, Xiaoping Sun, Pauline M. Chou*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Primary alveolar rhabdomyosarcoma (RMS) involving perineal skin is extremely rare, particularly in the infant age group. We report a case of an alveolar RMS in a newborn with abnormal symmetrical perineal overgrowth, causing ambiguous morphologic structure of the genitalia. Clinical and imaging studies were suggestive of Proteus syndrome with lymphatic malformation. Histologic examination of the mass showed cutaneous alveolar RMS with areas of embryonal and pleomorphic RMS features. Multiple superficially located, cystic-dilated spaces with loose edematous-mucoid hypocellular stroma gave a gross morphologic structure similar to that of lymphatic-type excrescences.

Original languageEnglish (US)
Pages (from-to)982-984
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Issue number8
StatePublished - Aug 2002

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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