Primary cutaneous lymphomas: A review with current treatment options

Christiane Querfeld, Joan Guitart, Timothy M. Kuzel, Steven T. Rosen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Primary cutaneous T- and B-cell lymphomas are a heterogenous group of diseases with varied clinical presentations and prognosis. The use of new molecular, histological, and clinical criteria have enhanced the recognition of primary cutaneous T- and B-cell lymphomas. Compared to their nodal counterpart they have a different clinical behavior and therefore require a different treatment approach. Independent predictive factors identified clinically, histologically, and by immunopheno- and immunogenotyping are essential to assess the appropriate treatment for each subtype. The European Organization for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Study Group provide a classification of cutaneous lymphomas taking into account of the histological and molecular features. Based on this classification we will provide a summary of the current medical literature in diagnosis, treatment, and prognosis for primary cutaneous lymphomas with emphasis on new treatment strategies.

Original languageEnglish (US)
Pages (from-to)131-142
Number of pages12
JournalBlood Reviews
Volume17
Issue number3
DOIs
StatePublished - Jan 1 2003

Keywords

  • Clinicopathologic correlations
  • Primary cutaneous lymphoma
  • Prognostic indices
  • Treatment

ASJC Scopus subject areas

  • Hematology
  • Oncology

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