Primary intracranial dural-based synovial sarcoma with an unusual SYT fluorescence in situ hybridization pattern: Case report

Craig Horbinski*, Kathleen Cieply, Ghassan K. Bejjani, Kathryn McFadden

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The authors present the case of an elderly man with a primary dural-based intracranial synovial sarcoma. Histological and immunohistochemical profiles of the lesion were diagnostic for a synovial sarcoma, and molecular studies using fluorescence in situ hybridization were compatible with a synovial sarcoma. A wide array of spindle cell neoplasms has been described as originating in the dura. To the authors' knowledge, however, this is only the second primary dura-based intracranial synovial sarcoma ever reported, emphasizing the importance of abroad differential diagnosis when encountering spindle cell lesions of the meninges.

Original languageEnglish (US)
Pages (from-to)897-903
Number of pages7
JournalJournal of neurosurgery
Volume109
Issue number5
DOIs
StatePublished - Nov 1 2008

Keywords

  • Dura
  • Spindle cell neoplasm
  • Synovial sarcoma
  • Translocation

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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