TY - JOUR
T1 - Primary intratesticular spindle cell tumors
T2 - Interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor
AU - Nistal, Manuel
AU - Gonzalez-Peramato, Pilar
AU - Serrano, Alvaro
AU - Reyes-Mugica, Miguel
AU - Cajaiba, Mariana M.
PY - 2011/2/1
Y1 - 2011/2/1
N2 - Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special techniques are needed. The present study reports 2 unusual cases of primary intratesticular tumors showing a striking morphology, characterized by spindle to stellate cells in a lymphoid background. The diagnosis of interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor was established in the 2 cases, and their probable origin in cells of the accessory immune system is discussed. Although both tumors share similar histological features, their immunohistochemical profiles were decisive for a definitive diagnosis.
AB - Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special techniques are needed. The present study reports 2 unusual cases of primary intratesticular tumors showing a striking morphology, characterized by spindle to stellate cells in a lymphoid background. The diagnosis of interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor was established in the 2 cases, and their probable origin in cells of the accessory immune system is discussed. Although both tumors share similar histological features, their immunohistochemical profiles were decisive for a definitive diagnosis.
KW - accessory immune system
KW - inflammatory myofibroblastic tumor
KW - interdigitating dendritic cell tumor
KW - testicular spindle cell neoplasms
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U2 - 10.1177/1066896908323505
DO - 10.1177/1066896908323505
M3 - Article
C2 - 18805870
AN - SCOPUS:79551671948
SN - 1066-8969
VL - 19
SP - 104
EP - 109
JO - International Journal of Surgical Pathology
JF - International Journal of Surgical Pathology
IS - 1
ER -