Primary malignant melanoma of the common bile duct: A case report and review of the literature

Monica S. Wagner, Margo Shoup, Jack Pickleman, Sherri Yong*

*Corresponding author for this work

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Primary malignant melanoma of the common bile duct is rare. To our knowledge, only 6 cases have been reported previously. The pathologic diagnosis of primary malignant melanoma in extracutaneous sites often requires the use of confirmatory immunohistochemical stains and electron microscopy studies, as well as tests to rule out other possible remote or concurrent primary sites. The presence of junctional activity adjacent to the tumor is another important requisite for the diagnosis of this entity. Nevertheless, absolute exclusion of a metastatic melanoma from an unknown occult site or regressed site is not entirely possible. We describe our observations in a case of primary malignant melanoma of the common bile duct in a 48-year-old man and discuss the criteria for diagnosis of primary melanoma.

Original languageEnglish (US)
Pages (from-to)419-422
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume124
Issue number3
StatePublished - Mar 27 2000

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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