Primary nephrotic syndrome of childhood

H. William Schnaper*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Primary nephrotic syndrome encompasses the spectrum of minimal change disease, focal segmental glomerulosclerosis, and related disorders. It is a common cause of morbidity and, more rarely, of mortality in children. Recent progress has premitted us to better understand the mechanism of proteinuria and how it causes the other findings of nephrotic. Developments related to the pathogenesis of nephrosis and why some patients develop focal segmental glomerulosclerosis are less striking, but recent studies have indicated useful directions for subsequent work in these areas. Finally, application of newer concepts to treatment has provided both a better prognosis for these diseases and decreased morbidity from treatment.

Original languageEnglish (US)
Pages (from-to)141-147
Number of pages7
JournalCurrent opinion in pediatrics
Issue number2
StatePublished - 1996

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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