TY - JOUR
T1 - Primary sclerosing cholangitis in the presence of a lupus anticoagulant
AU - Kirby, Donald F.
AU - Blei, Andres T.
AU - Rosen, Steven T.
AU - Vogelzang, Robert L.
AU - Neiman, Harvey L.
PY - 1986/12
Y1 - 1986/12
N2 - Lupus anticoagulant, an immunoglobulin that prolongs the partial thromboplastin time, has been associated with thrombotic events, including deep venous thrombosis, pulmonary emboli, and Budd-Chiari syndrome. In this report, primary sclerosing cholangitis was diagnosed in a man with a 10-year history of multiple thrombotic events related to a circulating lupus anticoagulant. Progressive jaundice and pruritus developed, and sclerosing cholangitis was confirmed by direct cholangiography. Sclerosing cholangitis is the second hepatobiliary disease reported in association with a lupus anticoagulant.
AB - Lupus anticoagulant, an immunoglobulin that prolongs the partial thromboplastin time, has been associated with thrombotic events, including deep venous thrombosis, pulmonary emboli, and Budd-Chiari syndrome. In this report, primary sclerosing cholangitis was diagnosed in a man with a 10-year history of multiple thrombotic events related to a circulating lupus anticoagulant. Progressive jaundice and pruritus developed, and sclerosing cholangitis was confirmed by direct cholangiography. Sclerosing cholangitis is the second hepatobiliary disease reported in association with a lupus anticoagulant.
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U2 - 10.1016/0002-9343(86)90412-2
DO - 10.1016/0002-9343(86)90412-2
M3 - Article
C2 - 3099567
AN - SCOPUS:0023027990
SN - 0002-9343
VL - 81
SP - 1077
EP - 1080
JO - The American journal of medicine
JF - The American journal of medicine
IS - 6
ER -