Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy

Madhura A. Tamhankar; Nicholas J. Volpe; Laurie A. Loevner; James N. Palmer; Michael Feldman

doi:10.1097/WNO.0b013e31814b1a7b

Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy

Madhura A. Tamhankar, Nicholas J. Volpe^*, Laurie A. Loevner, James N. Palmer, Michael Feldman

^*Corresponding author for this work

Ophthalmology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.

Original language	English (US)
Pages (from-to)	189-192
Number of pages	4
Journal	Journal of Neuro-Ophthalmology
Volume	27
Issue number	3
DOIs	https://doi.org/10.1097/WNO.0b013e31814b1a7b
State	Published - Sep 1 2007

ASJC Scopus subject areas

Ophthalmology
Clinical Neurology

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title = "Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy",

abstract = "A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.",

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T1 - Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy

AU - Tamhankar, Madhura A.

AU - Volpe, Nicholas J.

AU - Loevner, Laurie A.

AU - Palmer, James N.

AU - Feldman, Michael

PY - 2007/9/1

Y1 - 2007/9/1

N2 - A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.

AB - A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.

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Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy

Abstract

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