Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy

Madhura A. Tamhankar, Nicholas J. Volpe*, Laurie A. Loevner, James N. Palmer, Michael Feldman

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Scopus citations


A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.

Original languageEnglish (US)
Pages (from-to)189-192
Number of pages4
JournalJournal of Neuro-Ophthalmology
Issue number3
StatePublished - Sep 1 2007


ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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