PRISM: A Progenitor-Restricted Intersectional Fate Mapping Approach Redefines Forebrain Lineages

Jean François Poulin, Milagros Pereira Luppi, Caitlyn Hofer, Giuliana Caronia, Pei Ken Hsu, C. Savio Chan, Rajeshwar Awatramani*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Understanding the lineage of the diverse neuronal populations of the CNS is a complex but critical task. Poulin et al. present PRISM, an approach that facilitates recombinase-based lineage analysis. Using PRISM, the authors redefined the lineages of key forebrain progenitor populations.

Original languageEnglish (US)
Pages (from-to)740-753.e3
JournalDevelopmental Cell
Volume53
Issue number6
DOIs
StatePublished - Jun 22 2020

Keywords

  • Cux2
  • Sonic hedgehog
  • development
  • fate mapping
  • forebrain
  • intersectional genetics
  • lineage
  • neuron
  • progenitor
  • recombinase

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'PRISM: A Progenitor-Restricted Intersectional Fate Mapping Approach Redefines Forebrain Lineages'. Together they form a unique fingerprint.

  • Cite this