Probing cytoskeleton dynamics with multi-directional topographical guidance

Junyu Mai, Cheng Sun, Song Li, Xiang Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We used microfabricated topographical guidance to manipulate the organization of a single cell cytoskeleton, and to probe a cell from multiple directions to study the molecular mechanisms regulating the coordination process of cell migration.

Original languageEnglish (US)
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages610-612
Number of pages3
ISBN (Electronic)9780979806407
StatePublished - 2007
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: Oct 7 2007Oct 11 2007

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/TerritoryFrance
CityParis
Period10/7/0710/11/07

Funding

This work was supported by the Center for Cell Mimetic Space Exploration and NSF Nanoscale Science and Engineering Center. J. M. is supported by NSF-IGERT Fellowship. This work was supported by the Center for Cell Mimetic Space Exploration and SN F Nanoscale Science and Engineering Center. J. M. is supported by NSF-IGERT Fellowship.

Keywords

  • Cell migration
  • Contact guidance
  • Single cell manipulation
  • Surface topography

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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