Abstract
A formidable synthetic apparatus for the creation of nanoscale molecular structures and supramolecular assemblies through molecular structures can potentially be created from systems that are capable of parallel automultiplication (self-replication). In order to achieve this goal, a detailed understanding of the relationship be tween molecular structure and replication efficiency is necessary. Diastereoisomeric templates that are capable of specific and simultaneous autocatalysis have been synthesised. A systematic experimental and theoretical evaluation of their behaviour and that of structurally-related systems reveals the key determinants that dictate the emergence of self-replicative function and defines the structural space within which this behaviour is observed.
Original language | English (US) |
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Pages (from-to) | 8798-8812 |
Number of pages | 15 |
Journal | Chemistry - A European Journal |
Volume | 12 |
Issue number | 34 |
DOIs | |
State | Published - Nov 24 2006 |
Keywords
- Kinetics
- Molecular recognition
- Recognition-mediated reactions
- Self-replication
- Supramolecular chemistry
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry