@article{26f166227f254c7db11f80f1610becbd,
title = "Probing the Consequences of Cubic Particle Shape and Applied Field on Colloidal Crystal Engineering with DNA",
abstract = "In a magnetic field, cubic Fe3O4 nanoparticles exhibit assembly behavior that is a consequence of a competition between magnetic dipole–dipole and ligand interactions. In most cases, the interactions between short hydrophobic ligands dominate and dictate assembly outcome. To better tune the face-to-face interactions, cubic Fe3O4 nanoparticles were functionalized with DNA. Their assembly behaviors were investigated both with and without an applied magnetic field. Upon application of a field, the tilted orientation of cubes, enabled by the flexible DNA ligand shell, led to an unexpected crystallographic alignment of the entire superlattice, as opposed to just the individual particles, along the field direction as revealed by small and wide-angle X-ray scattering. This observation is dependent upon DNA length and sequence and cube dimensions. Taken together, these studies show how combining physical and chemical control can expand the possibilities of crystal engineering with DNA.",
keywords = "DNA, crystal engineering, magnetic materials, nanoparticles, self-assembly",
author = "Urbach, {Zachary J.} and Park, {Sarah S.} and Weigand, {Steven L.} and Rix, {James E.} and Byeongdu Lee and Mirkin, {Chad A.}",
note = "Funding Information: This work was supported as part of the Center for Bio‐Inspired Energy Science, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under award DE‐SC0000989 (colloidal crystal assembly under magnetic field), and the Air Force Office of Scientific Research award FA9550‐17‐1‐0348 (oligonucleotide synthesis and purification and DNA‐functionalization of FeO NPs). SAXS studies were performed at the DuPont‐Northwestern‐Dow Collaborative Access Team (DND‐CAT) located at Sector 5 of the Advanced Photon Source (APS). DND‐CAT is supported by Northwestern University, the Dow Chemical Company, and DuPont de Nemours, Inc. This research used resources of the APS, a U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE‐AC02‐06CH11357. Z.J.U. gratefully acknowledges support from the National Defense Science and Engineering Graduate Fellowship. This work made use of the Electron Probe Instrumentation Center and BioCryo facilities of Northwestern University's NUANCE Center, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS‐1542205); the Northwestern University Materials Research Science and Engineering Center (NU‐MRSEC) (NSF DMR‐1720139); the International Institute for Nanotechnology (IIN); the Keck Foundation; and the State of Illinois, through the IIN. Metal analysis was performed at the Northwestern University Quantitative Bio‐element Imaging Center. The authors thank J. Bussan for magnetic stage setup and E. W. Roth for helpful discussions about electron tomography. 3 4 Publisher Copyright: {\textcopyright} 2020 Wiley-VCH GmbH",
year = "2021",
month = feb,
day = "19",
doi = "10.1002/anie.202012907",
language = "English (US)",
volume = "60",
pages = "4065--4069",
journal = "Angewandte Chemie - International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "8",
}