Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: Comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2′-O-ribonucleic acid modifications

Martin Egli*, George Minasov, Valentina Tereshko, Pradeep S. Pallan, Marianna Teplova, Gopal B. Inamati, Elena A. Lesnik, Steve R. Owens, Bruce S. Ross, Thazha P. Prakash, Muthiah Manoharan

*Corresponding author for this work

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Medicine & Life Sciences

Chemical Compounds