Probiotics and prevention of Clostridium difficile infection

E. J.C. Goldstein; S. J. Johnson; P. J. Maziade; C. T. Evans; J. C. Sniffen; M. Millette; L. V. McFarland

doi:10.1016/j.anaerobe.2016.12.007

Probiotics and prevention of Clostridium difficile infection

E. J.C. Goldstein^*, S. J. Johnson, P. J. Maziade, C. T. Evans, J. C. Sniffen, M. Millette, L. V. McFarland

^*Corresponding author for this work

Preventive Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, Lactobacillus rhamnosus CLR2 (Bio-K+).

Original language	English (US)
Pages (from-to)	114-119
Number of pages	6
Journal	Anaerobe
Volume	45
DOIs	https://doi.org/10.1016/j.anaerobe.2016.12.007
State	Published - Jun 2017

Keywords

Bio-K+
C. difficile
Lactobacillus acidophilus CL1285
Lactobacillus casei LBC80R
Lactobacillus rhamnosus CLR2
Lactobacillus rhamnosus GG
Probiotic
Saccharomyces boulardii

ASJC Scopus subject areas

Microbiology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.anaerobe.2016.12.007

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title = "Probiotics and prevention of Clostridium difficile infection",

abstract = "The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, Lactobacillus rhamnosus CLR2 (Bio-K+).",

keywords = "Bio-K+, C. difficile, Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, Lactobacillus rhamnosus CLR2, Lactobacillus rhamnosus GG, Probiotic, Saccharomyces boulardii",

author = "Goldstein, {E. J.C.} and Johnson, {S. J.} and Maziade, {P. J.} and Evans, {C. T.} and Sniffen, {J. C.} and M. Millette and McFarland, {L. V.}",

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year = "2017",

month = jun,

doi = "10.1016/j.anaerobe.2016.12.007",

language = "English (US)",

volume = "45",

pages = "114--119",

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AU - Goldstein, E. J.C.

AU - Johnson, S. J.

AU - Maziade, P. J.

AU - Evans, C. T.

AU - Sniffen, J. C.

AU - Millette, M.

AU - McFarland, L. V.

PY - 2017/6

Y1 - 2017/6

N2 - The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, Lactobacillus rhamnosus CLR2 (Bio-K+).

AB - The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, Lactobacillus rhamnosus CLR2 (Bio-K+).

KW - Bio-K+

KW - C. difficile

KW - Lactobacillus acidophilus CL1285

KW - Lactobacillus casei LBC80R

KW - Lactobacillus rhamnosus CLR2

KW - Lactobacillus rhamnosus GG

KW - Probiotic

KW - Saccharomyces boulardii

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JO - Anaerobe

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Probiotics and prevention of Clostridium difficile infection

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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