Process development for high-resolution 3D-printing of bioresorbable vascular stents

Henry Oliver T. Ware; Adam C. Farsheed; Robert Van Lith; Evan Baker; Guillermo Ameer; Cheng Sun

doi:10.1117/12.2252856

Process development for high-resolution 3D-printing of bioresorbable vascular stents

Henry Oliver T. Ware^*, Adam C. Farsheed, Robert Van Lith, Evan Baker, Guillermo Ameer, Cheng Sun

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

6 Scopus citations

Abstract

The recent development of "continuous projection microstereolithography" also known as CLIP technology has successfully alleviated the main obstacles surrounding 3D printing technologies: Production speed and part quality. Following the same working principle, we further developed the μCLIP process to address the needs for high-resolution 3D printing of biomedical devices with micron-scale precision. Compared to standard stereolithography (SLA) process, μCLIP fabrication can reduce fabrication time from several hours to as little as a few minutes. μCLIP can also produce better surface finish and more uniform mechanical properties than conventional SLA, as each individual "fabrication layer" continuously polymerizes into the subsequent layer. In this study, we report the process development in manufacturing high-resolution bioresorbable stents using our own μCLIP system. The bioresorbable photopolymerizable biomaterial (B-ink) used in this study is methacrylated poly(1, 12 dodecamethylene citrate) (mPDC). Through optimization of our μCLIP process and concentration of B-ink components, we have created a customizable bioresorbable stent with similar mechanical properties exhibited by nitinol stents. Upon optimization, fabricating a 2 cm tall vascular stent that comprises 4000 layers was accomplished in 26.5 minutes.

Original language	English (US)
Title of host publication	Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017
Editors	Winston V. Schoenfeld, Georg von Freymann, Raymond C. Rumpf
Publisher	SPIE
ISBN (Electronic)	9781510606715
DOIs	https://doi.org/10.1117/12.2252856
State	Published - Jan 1 2017
Event	Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017 - San Francisco, United States Duration: Jan 29 2017 → Feb 1 2017

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	10115
ISSN (Print)	0277-786X
ISSN (Electronic)	1996-756X

Other

Other	Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017
Country	United States
City	San Francisco
Period	1/29/17 → 2/1/17

Keywords

3D Printing
Bioresorbable Vascular Stent
μCLIP

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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Ware, H. O. T., Farsheed, A. C., Van Lith, R., Baker, E., Ameer, G., & Sun, C. (2017). Process development for high-resolution 3D-printing of bioresorbable vascular stents. In W. V. Schoenfeld, G. von Freymann, & R. C. Rumpf (Eds.), Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017 [101150N] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 10115). SPIE. https://doi.org/10.1117/12.2252856

Ware, Henry Oliver T. ; Farsheed, Adam C. ; Van Lith, Robert ; Baker, Evan ; Ameer, Guillermo ; Sun, Cheng. / Process development for high-resolution 3D-printing of bioresorbable vascular stents. Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017. editor / Winston V. Schoenfeld ; Georg von Freymann ; Raymond C. Rumpf. SPIE, 2017. (Proceedings of SPIE - The International Society for Optical Engineering).

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abstract = "The recent development of {"}continuous projection microstereolithography{"} also known as CLIP technology has successfully alleviated the main obstacles surrounding 3D printing technologies: Production speed and part quality. Following the same working principle, we further developed the μCLIP process to address the needs for high-resolution 3D printing of biomedical devices with micron-scale precision. Compared to standard stereolithography (SLA) process, μCLIP fabrication can reduce fabrication time from several hours to as little as a few minutes. μCLIP can also produce better surface finish and more uniform mechanical properties than conventional SLA, as each individual {"}fabrication layer{"} continuously polymerizes into the subsequent layer. In this study, we report the process development in manufacturing high-resolution bioresorbable stents using our own μCLIP system. The bioresorbable photopolymerizable biomaterial (B-ink) used in this study is methacrylated poly(1, 12 dodecamethylene citrate) (mPDC). Through optimization of our μCLIP process and concentration of B-ink components, we have created a customizable bioresorbable stent with similar mechanical properties exhibited by nitinol stents. Upon optimization, fabricating a 2 cm tall vascular stent that comprises 4000 layers was accomplished in 26.5 minutes.",

keywords = "3D Printing, Bioresorbable Vascular Stent, μCLIP",

author = "Ware, {Henry Oliver T.} and Farsheed, {Adam C.} and {Van Lith}, Robert and Evan Baker and Guillermo Ameer and Cheng Sun",

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Ware, HOT, Farsheed, AC, Van Lith, R, Baker, E, Ameer, G & Sun, C 2017, Process development for high-resolution 3D-printing of bioresorbable vascular stents. in WV Schoenfeld, G von Freymann & RC Rumpf (eds), Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017., 101150N, Proceedings of SPIE - The International Society for Optical Engineering, vol. 10115, SPIE, Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017, San Francisco, United States, 1/29/17. https://doi.org/10.1117/12.2252856

Process development for high-resolution 3D-printing of bioresorbable vascular stents. / Ware, Henry Oliver T.; Farsheed, Adam C.; Van Lith, Robert; Baker, Evan; Ameer, Guillermo ; Sun, Cheng.

Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017. ed. / Winston V. Schoenfeld; Georg von Freymann; Raymond C. Rumpf. SPIE, 2017. 101150N (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 10115).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Process development for high-resolution 3D-printing of bioresorbable vascular stents

AU - Ware, Henry Oliver T.

AU - Farsheed, Adam C.

AU - Van Lith, Robert

AU - Baker, Evan

AU - Ameer, Guillermo

AU - Sun, Cheng

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AB - The recent development of "continuous projection microstereolithography" also known as CLIP technology has successfully alleviated the main obstacles surrounding 3D printing technologies: Production speed and part quality. Following the same working principle, we further developed the μCLIP process to address the needs for high-resolution 3D printing of biomedical devices with micron-scale precision. Compared to standard stereolithography (SLA) process, μCLIP fabrication can reduce fabrication time from several hours to as little as a few minutes. μCLIP can also produce better surface finish and more uniform mechanical properties than conventional SLA, as each individual "fabrication layer" continuously polymerizes into the subsequent layer. In this study, we report the process development in manufacturing high-resolution bioresorbable stents using our own μCLIP system. The bioresorbable photopolymerizable biomaterial (B-ink) used in this study is methacrylated poly(1, 12 dodecamethylene citrate) (mPDC). Through optimization of our μCLIP process and concentration of B-ink components, we have created a customizable bioresorbable stent with similar mechanical properties exhibited by nitinol stents. Upon optimization, fabricating a 2 cm tall vascular stent that comprises 4000 layers was accomplished in 26.5 minutes.

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KW - Bioresorbable Vascular Stent

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Ware HOT, Farsheed AC, Van Lith R, Baker E, Ameer G , Sun C. Process development for high-resolution 3D-printing of bioresorbable vascular stents. In Schoenfeld WV, von Freymann G, Rumpf RC, editors, Advanced Fabrication Technologies for Micro/Nano Optics and Photonics X 2017. SPIE. 2017. 101150N. (Proceedings of SPIE - The International Society for Optical Engineering). https://doi.org/10.1117/12.2252856