Production and Systemic Absorption of Toxic Byproducts of Tissue Combustion during Laparoscopic Cholecystectomy

Justin S. Wu, Terri Monk, Donna R. Luttmann, Thomas A. Meininger, Nathaniel J. Soper*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Among the potential hazards of laparoscopic surgery using electrocautery is the release of chemical byproducts of incomplete tissue combustion into the pneumoperitoneum with subsequent transpentoneal absorption into the bloodstream and/or release into the operating room. The purpose of this study of patients undergoing laparoscopic cholecystectomy (LC) was twofold (1) to assess the relationship between intraperitoneal concentration of carbon monoxide (CO) and blood levels of carboxyhemoglobin (COHb) and methemoglobin (MetHb), and (2) to assess the surgeon's inhalation of CO resulting from ambient smoke exposure During LC with monopolar electrocautery, 21 patients were evaluated intraoperatively for intraperitoneal [CO] by sampling gas from a trocar, whereas arterial [COHb] and [MetHb] were determined penoperatively The surgeon's venous blood was drawn pre- and postoperatively to assay [COHb] and [MetHb] Patients completed visual analogue questionnaires 6 hours and 24 hours postoperatively to assess for adverse symptoms Mean (± SEM) patient age and weight were 45 ± years and 84 ± 4 kg, respectively Mean duration of the operation was 69 ± 5 minutes, and electrocautery was used for 3 0 ± 0 3 minutes Intraperitoneal [CO] rose to peak levels of 209 ± 19 ppm at 50 minutes, whereas systemic [COHb] and [MetHb] were unchanged The surgeon's systemic [COHb] and [MetHb] did not increase postoperatively Nausea, abdominal pain, and fatigue scores decreased significantly between 6 and 24 hours postoperatively, however, there were no correlations between these symptoms and peak mtrapentoneal [CO] Although LC using electrocautery increases intraperitoneal [CO] to "hazardous" levels, systemic [COHb] and [MetHb] are not elevated by generation of intraperitoneal smoke The surgeon's exposure to CO by the evacuation of smoke through laparoscopic ports is negligible Production of smoke during LC using monopolar electrocautery, therefore, does not appear to pose a threat to either the patient or the surgeon.

Original languageEnglish (US)
Pages (from-to)399-405
Number of pages7
JournalJournal of Gastrointestinal Surgery
Volume2
Issue number5
DOIs
StatePublished - 1998

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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