Prognostic significance of ST-segment depression on continuous electrocardiography in patients with acute ischemic neurologic events

Mary Mc Grae McDermott*, Frank Lefevre, Martin Arron, John Foley, Gary J. Martin, José Biller

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Patients with a history of ischemic stroke or transient ischemic attack (TIA) are at significant risk of cardiac death. This study reports the prognostic significance of ST-segment depression and ventricular tachycardia on continuous electrocardiography in 48 consecutive patients hospitalized with an acute ischemic stroke or TIA. Thirty-one percent of patients had episodes of asymptomatic ST-segment depression and 6% had transient ventricular tachycardia on continuous electrocardiographic monitoring. At a mean follow-up of 13 months, 19% had experienced a cardiac outcome, and 19% met criteria for a neurologic outcome. Cardiac and neurologic outcomes, including death, were not significantly different in patients with and without ST-segment depression on continuous electrocardiography. Cardiac outcomes occurred in 13% of patients with ST-segment depression and in 21% of patient without ST-segment depression (p = 0.52). However, ventricular tachycardia was associated with a higher rate of cardiac death (33% vs. 2%, p < 0.01). Only 27% of patients subsequently found to have coronary artery disease had ST-segment depression by continuous electrocardiography. In contrast to patients with coronary artery disease, ST-segment depression on continuous electrocardiography is not associated with poorer outcome among patients with acute ischemic stroke or TIA.

Original languageEnglish (US)
Pages (from-to)180-184
Number of pages5
JournalJournal of Stroke and Cerebrovascular Diseases
Volume5
Issue number3
DOIs
StatePublished - Jan 1 1995

Keywords

  • Cerebral ischemia
  • Cerebrovascular outcomes
  • Coronary heart disease
  • Electrocardiography

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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