Programmable shape-shifting micelles

Miao Ping Chien*, Anthony M. Rush, Matthew P. Thompson, Nathan C. Gianneschi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

178 Scopus citations

Abstract

Getting in shape: DNA-brush copolymer amphiphiles assemble into micelles with morphologies determined by selective interactions that allow manipulation of the magnitude of steric and electrostatic repulsions in the micelle shells. Cylinder-to-sphere phase transitions occur when an input DNA sequence is added to the micelles (see picture).

Original languageEnglish (US)
Pages (from-to)5076-5080
Number of pages5
JournalAngewandte Chemie - International Edition
Volume49
Issue number30
DOIs
StatePublished - Jul 12 2010

Keywords

  • Aggregation
  • Amphiphiles
  • Block copolymers
  • DNA
  • Micelles

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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