Programs and processes for advancing pediatric acute kidney support therapy in hospitalized and critically ill children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference

the ADQI 26 workgroup

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Pediatric acute kidney support therapy (paKST) programs aim to reliably provide safe, effective, and timely extracorporeal supportive care for acutely and critically ill pediatric patients with acute kidney injury (AKI), fluid and electrolyte derangements, and/or toxin accumulation with a goal of improving both hospital-based and lifelong outcomes. Little is known about optimal ways to configure paKST teams and programs, pediatric-specific aspects of delivering high-quality paKST, strategies for transitioning from acute continuous modes of paKST to facilitate rehabilitation, or providing effective short- and long-term follow-up. As part of the 26th Acute Disease Quality Initiative Conference, the first to focus on a pediatric population, we summarize here the current state of knowledge in paKST programs and technology, identify key knowledge gaps in the field, and propose a framework for current best practices and future research in paKST.

Original languageEnglish (US)
Pages (from-to)993-1004
Number of pages12
JournalPediatric Nephrology
Volume39
Issue number3
DOIs
StatePublished - Mar 2024

Funding

The following individuals contributed to the formulation and content of this work in accordance with their participation in the 26th Acute Disease Quality Initiative (ADQI XXVI): Rashid Alobaidi1, Sean M. Bagshaw1, Matthew Barhight2, Erin Barreto3, O.N. Ray Bignall II4, Erica Bjornstad5, Patrick Brophy6, Jennifer Charlton7, Andrea L. Conroy8, Prasad Devarajan9, Kristin Dolan10, Dana Fuhrman11, Katja M. Gist9, Stephen M. Gorga12, Jason H. Greenberg13, Denise Hasson9, Emma Heydari1, Arpana Iyengar14, Jennifer Jetton15, Catherine Krawczeski4, Leslie Meigs15, Shina Menon16, Catherine Morgan1, Theresa Mottes2, Zaccaria Ricci17, David T. Selewski18, Danielle Soranno8, Natalja Stanski9, Michelle Starr8, Scott M. Sutherland19, Jordan Symons16, Marcelo Tavares20, Molly Vega21, Michael Zappitelli22, Claudio Ronco23, Ravindra L. Mehta24, John Kellum25, Marlies Ostermann.261Alberta Health Sciences University, Edmonton, Alberta, Canada.2Northwestern University Feinberg School of Medicine, Ann & Robert Lurie Children’s Hospital of Chicago, Chicago, IL, USA.3Mayo Clinic, Rochester, MN, USA.4Nationwide Children’s Hospital, Ohio State University, Columbus, OH, USA.5Children’s Hospital Alabama, Birmingham, AL, USA.6Golisano Children’s Hospital, Rochester University Medical Center, Rochester, NY, USA.7University of Virginia, Charlottesville, VA, USA.8Riley Children’s Hospital, Indiana University School of Medicine, Indianapolis, IN, USA.9Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.10Mercy Children’s Hospital, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.11Children’s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.12C.S. Mott Children’s Hospital, University of Michigan, Ann Arbor, MI, USA.13Yale University Medical Center, New Haven, CT, USA.14St. John’s National Academy of Health Sciences, Bangalore, India.15Stead Family Children’s Hospital, University of Iowa, Iowa City, IA, USA.16Seattle Children’s Hospital, University of Washington, Seattle, WA, USA.17University of Florence, Florence, Italy.18Medical University of South Carolina, Charleston, SC, USA.19Lucille Packard Children’s Hospital, Stanford University, Palo Alto, CA, USA.20Santa Casa dela Belo Horizonte, Belo Horizonte, Brazil.21Texas Children’s Hospital, Baylor College of Medicine, Houston, TX, USA.22Hospital for Sick Children, Toronto, Ontario, Canada.23San Bartolo Hospital, Universiti di Padova, Vicenza, Italy.24University of California San Diego School of Medicine, La Jolla, CA, USA.25University of Pittsburgh Medical Center, Pittsburgh, PA, USA.26Guy’s and St. Thomas’ NHS Foundation Trust, London, UK.

Keywords

  • AKI
  • CRRT
  • CVVH
  • Children
  • Critical care
  • Dialysis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

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